Frank is the founder and CEO of Lisa Frank Incorporated. After moving from the Detroit, Michigan, area to Tucson Arizona, in the 1970s to study art at the University of Arizona, she founded the children’s jewelry company Sticky Fingers, which became Lisa Frank Inc. circa 1979 when she was 24. She continues to lead it as of 2019. Her corporation’s artwork features rainbow and neon colors and stylized depictions of animals, including dolphins, pandas, and unicorns. In the 1980s and 1990s, her products – including school supplies such as lunchboxes and Trapper Keepers, as well as toys and stickers – were popular among elementary and middle school-aged girls. The company’s headquarters is in Tucson, Arizona. The company no longer produces its own products and as of at least 2018 licenses its name to smaller companies.